Drug repurposing
Drug repurposing is when drugs that are in use for a specific disease or condition are identified as having therapeutic use in a different disease.
There are no FDA-approved drugs (or the equivalent in non-US countries) for the treatment of ME/CFS, so clinical management of the disease typically relies on repurposing drugs in addition to lifestyle modifications like pacing. Research into treatments also often utilize drug repurposing because trials on repurposed drugs are generally cheaper and faster than developing a new drug.
OMF’s clinical trial, the Life Improvement Trial (LIFT), is testing two repurposed drugs: low-dose naltrexone and pyridostigmine. Read more about the study on our website: https://www.omf.ngo/the-life-improvement-trial/.